Author: Yaovi Mignazonzon AFASSINOU , Bassimssouwé SOLI, Soulemane PESSINABA, Nansirine OLOUDE, Borgatia ATTA, Komlavi YAYEHD, Machihude PIO, Soodougoua BARAGOU, Findibe DAMOROU

Manuscript ID: AFMJ-Aug-2025-24 Date Published: 2025-09-01 11:55:11

Background:

Heart failure (HF) is the natural course of many heart conditions. It is often associated with comorbidities. In Togo, comorbidities in heart failure and their impact remain unknown. The aim of our study was to provide a description of the characteristics of HF and associated comorbidities and the effect of comorbidities on hospitalized HF patients in the cardiology department of the Sylvanus Olympio Teaching Hospital (CHU SO).

Methods:

This was a retrospective study of the medical records of patients with HF who were admitted to the CHU SO’s cardiology department, from January 1, 2018, to July 31, 2022. Incomplete records were excluded. The study was conducted with 598 participants. The data were analysed with EpiInfo software version 7.2.5.0. The relationships between comorbidities and adverse HF outcomes were examined using both univariate and multivariate logistic regression methods. The statistical significance threshold was p<0.05.

Results:

The admission rate of HF was 32.2%. The mean age of the patients was 51.4 ± 17.7 years. In 71.7% of cases, HF advanced chronically. The main extracardiac comorbidities were pneumonia (31.8%), renal failure (29.3%), hypokalemia (28.4%) and anaemia (25.1%). The comorbidity rate for HF patients with adverse outcomes was greater (3.46 ± 1.43) than that for HF patients without adverse outcomes (2.72 ± 1.83) (p<0.01). The adverse outcomes of HF were statistically linked to atrial fibrillation (p<0.01), hyperuricaemia (p=0.01), hyponatraemia (p=0.01), and pneumonia (p<0.01).

Conclusion:

HF is associated with many comorbidities. Atrial fibrillation and pneumonia are predictors of adverse outcomes in our HF cohort.

Click the button below to get the complete manuscript